Application of MALDI-TOF mass spectrometry in clinical diagnostic microbiology
نویسندگان
چکیده
منابع مشابه
Application of MALDI-TOF mass spectrometry in clinical diagnostic microbiology.
Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently emerged as a powerful technique for identification of microorganisms, changing the workflow of well-established laboratories so that its impact on microbiological diagnostics has been unparalleled. In comparison with conventional identification methods that rely on biochemical tests and requ...
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Clinical microbiology laboratories today operate with the use of a blend of highand low-technology procedures. Despite huge steps forward in diagnostic methods based on nucleic acid amplification, clinical microbiology laboratories still rely heavily on culturing bacteria and fungi for diagnostic purposes. This process is typically done on solid (e.g., blood agar) and occasionally in liquid (i....
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Highlights 1. In October 2014, three DSM microbiology laboratories received MALDI-ToF instruments for identification of bacterial pathogens and will be implementing this technology in Winnipeg and Brandon over the next several months. 2. MALDI-ToF will result in decreased turnaround times for identification of pathogens, greater accuracy and lower costs of identification. 3. Combined with a pro...
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Recent EU directives and regulations for quality control and authentication of food products have prompted the development of new methods for large-scale tests to ensure the protection of consumers. In view of this, an innovative method based on MALDI-TOF mass spectrometry has been developed and successfully applied to fish authentication. Highly specific mass spectrometric profiles from 25 dif...
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MALDI-TOF mass spectrometry is a diagnostic tool of microbial identification and characterization based on the detection of the mass of molecules. In the majority of clinical laboratories, this technology is currently being used mainly for bacterial diagnosis, but several approaches in the field of virology have been investigated. The introduction of this technology in clinical virology will im...
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ژورنال
عنوان ژورنال: The Journal of Infection in Developing Countries
سال: 2014
ISSN: 1972-2680
DOI: 10.3855/jidc.3623